The scientific research project, "Measurement of porin-based antibiotic permeability using high-resolution terahertz time-domain spectroscopy," led by Associate Professor Fatma Doğan Güzel, a faculty member in the Department of Mechanical Engineering/Biomedical Engineering at our university's Faculty of Engineering and Natural Sciences, has been awarded funding by the Scientific and Technological Research Council of Turkey (TÜBİTAK) under the 2515-COST program.
The project, with a budget of approximately 2.4 million TL, is funded by TÜBİTAK under the "European Network for diagnosis and treatment of antibiotic-resistant bacterial infections (EURESTOP)-CA21145" action of the "2515-COST European Cooperation in Science and Technology Programme." The project aims to develop a new terahertz spectroscopy-based platform for analyzing antibiotic permeation pathways (porins) in Gram-negative bacteria. This fluorescence-free and rapid method will contribute to understanding resistance mechanisms and reducing unnecessary antibiotic use.
The project is supported by Dr. Aliakbar Ebrahimi, a postdoctoral researcher in our university's Biomedical Engineering Department; Prof. Dr. Cihan Darcan and Lecturer Dr. Özge Kaygusuz İzgördü from the Department of Molecular Biology and Genetics at Bilecik Şeyh Edebali University; and Assoc. Prof. Dr. Kholoud Elmabruk from the Department of Electrical and Electronics Engineering at Sivas University of Science and Technology. Prof. Dr. Asaf Behzat Şahın from the Department of Electrical and Electronics Engineering and Prof. Dr. Hakan Altan from the Department of Physics at Middle East Technical University will serve as project advisors.
This project, which will be carried out through the synergy of different disciplines (engineering, biophysics, microbiology), represents a radical solution to the problem of antibiotic resistance through the development of next-generation microfluidic and analytical platforms. This innovative approach aims to make significant contributions to our country's scientific research capacity and competitiveness in drug discovery and diagnostic technologies.
We congratulate our university's researchers and wish them continued success.
